Naltrexone & Vivitrol

Buprenorphine: Partial opioid agonist—contains opioid component, reduces cravings, allows some effect. Can start while using opioids. Longer treatment duration often needed.

Naltrexone: Pure antagonist—no opioid component, blocks cravings completely. Requires abstinence first. Works through blocking reward. Better for alcohol too.

Choose based on: addiction severity, motivation level, prior treatment response, whether treating alcohol, opioids, or both.

Yes. Starting naltrexone while taking opioids causes precipitated withdrawal—very uncomfortable. Most people need 7-10 days opioid-free. If heavy daily user, may need medical detoxification first. We support this process with medications and care.

You can—nothing prevents you physically. However, naltrexone blocks effects. Using produces no high, no reward, just expense and risk. This is naltrexone's power—removes motivation to use. Combined with therapy addressing underlying causes, this makes sustained recovery possible.

Yes. Naltrexone blocks both opioid and alcohol effects. If using both, naltrexone addresses both simultaneously. This is major advantage—one medication treats co-occurring addictions.

Varies. Some benefit from 6-12 months. Others continue longer. Unlike buprenorphine, naltrexone requires high motivation—people usually don't continue long-term unless actively engaged in recovery. Decision made collaboratively with your provider.

Most plans cover daily naltrexone. Vivitrol usually covered but may require prior authorization. We verify coverage and discuss cost-sharing. Financial assistance available if needed. Cost never prevents access to treatment.